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Home RX Products LINCOBIOTIC 600MG INJ (Lincomysin) – Epharma
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LINCOBIOTIC 600MG INJ (Lincomysin) – Epharma

Lincobiotic Injection 600mg/2ml (Lincomycin) – 

Lincobiotic Injection 600mg/2ml contains Lincomycin, a lincosamide class antibiotic used for the treatment of serious bacterial infections caused by susceptible bacteria. It works by inhibiting bacterial protein synthesis, thereby stopping bacterial growth and multiplication. Lincomycin binds to the 50S subunit of bacterial ribosomes, which prevents the formation of essential proteins required for bacterial survival.

Composition

Each 2ml ampoule contains:

Lincomycin Hydrochloride equivalent to Lincomycin 600mg
Dosage Form: Injection
Route of Administration: IM / IV (Intramuscular / Intravenous)

Uses & Indications

Lincobiotic Injection is used for the treatment of moderate to severe bacterial infections caused by susceptible organisms, particularly Gram-positive bacteria. It may be prescribed in infections where alternative antibiotics are not suitable or in patients with sensitivity to certain antibiotics.

It is commonly used in conditions such as:

Respiratory tract infections
Skin and soft tissue infections
Bone and joint infections
Ear, nose and throat infections
Dental infections
Certain anaerobic bacterial infections
Serious infections caused by susceptible Staphylococcus and Streptococcus species

How It Works

Lincomycin works by targeting bacterial protein production. It attaches to the bacterial ribosome and blocks protein synthesis, preventing bacteria from growing and spreading. This action helps the body’s immune system eliminate the infection.

Key Benefits
Effective lincosamide antibiotic therapy
Provides antibacterial activity against susceptible Gram-positive organisms
Suitable for IM and IV administration
Useful in serious bacterial infections requiring injectable antibiotic treatment
Helps control bacterial growth and infection progression
Dosage & Administration

The dose and duration of treatment depend on the type and severity of infection, patient’s age, weight, kidney/liver condition, and medical history.

Adults:

Dosage is determined by the healthcare professional based on infection severity.
Administration: Should only be administered by a qualified healthcare provider through intramuscular or intravenous routes.

Possible Side Effects

Some patients may experience:

Pain, redness, or irritation at injection site
Nausea or vomiting
Diarrhea
Abdominal discomfort
Skin rash or allergic reactions
Dizziness or headache

Severe or persistent diarrhea during treatment should be reported immediately, as antibiotic-associated colitis can occur with lincomycin therapy.

Precautions
Use only under the supervision of a doctor.
Inform your healthcare provider about any history of antibiotic allergy.
Complete the full prescribed course even if symptoms improve.
Avoid unnecessary antibiotic use to reduce the risk of antibiotic resistance.
Extra caution may be required in patients with liver disease or gastrointestinal disorders.

Storage

Store according to the manufacturer’s instructions. Protect from excessive heat, moisture, and direct sunlight.

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KENACOMB combines the potent corticosteroid triamcinolone acetonide with the antifungal antibiotic nystatin and the wide spectrum antibacterial activity of neomycin and gramicidin. KENACOMB reduces inflammation, relieves pruritis and combats or prevents monilial and bacterial infections. Pharmacokinetics The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin increase percutaneous absorption. Nystatin and gramicidin are not absorbed from intact skin or mucous membranes. Neomycin can be absorbed through inflamed skin. Once absorbed, it is rapidly excreted unchanged through the kidneys. The half-life is approximately 2 to 3 hours. Microbiology Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. Nystatin exhibits no activity against bacteria, protozoa, or viruses. Neomycin exerts its bacterial activity against a number of gram-negative organisms by inhibiting protein synthesis. It is not active against Pseudomonas aeruginosa, and resistant strains of gram-negative bacteria may develop. Gramicidin exerts its antibacterial activity against many gram-positive organisms by altering cell membrane permeability. INDICATIONS KENACOMB is indicated for use in corticosteroid responsive dermatoses complicated or threatened by secondary monilial and/or bacterial infections, such as: Atopic dermatitis Seborrhoeic dermatitis Lichen simplex chronicus Psoriasis (particularly of the face and body folds) Allergic contact dermatitis KENACOMB CREAM permits use in moist intertrigenous areas.
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