Phenergan 120ml Syrup ( Promethazine HCl ) SANOFI
How it works
It contain a medicine called promethazine hydrochloride. This belongs to a group of medicines called phenothiazines. It works by blocking a natural substance (histamine) that your body makes during an allergic reaction. It also works directly on the brain to help you feel more relaxed.
USAGE AND SAFETY
Dosage
Promethazine HCl
Side Effects
• Dry mouth, blurred vision or you cannot pass water (urine) • Feeling drowsy or sleepy, tiredness, disorientation, having nightmares, headaches, feeling restless • Loss of appetite (anorexia), indigestion • Feeling dizzy, lightheaded, faint (hypotension) • Feeling confused, especially in elderly people • Being more sensitive to the sun than usual. If this happens keep out of direct sunlight and do not use sun lamps • Unpleasant sensation or an overwhelming urge to move the legs (also called Restless Legs Syndrome).
Drug Interactions
• Some medicines for depression called monoamine oxidase inhibitors (MAOIs) • Anticholinergic medicines •Amitriptyline • Medicines to help you to sleep or feel more relaxed (such as diazepam or zolpidem) .
Indication
It is used to treat the following conditions: • For short term use: to treat adults with difficulty in sleeping (insomnia) • To treat allergic conditions such as hay fever or rashes (like nettle rash or hives) • To treat or stop you feeling sick (nausea) or being sick (vomiting) such as travel sickness • For short term use: as a sedative for children aged 5 years and above
When not to Use
Do not take this medicine if:The person taking the medicine is under 5 years of age ; You are allergic (hypersensitive) to promethazine hydrochloride or any of the other ingredients in the list ; The signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue.
PRECAUTIONS
Precaution
Use this medicine only as recommended. Do not exceed the recommended dose.
WARNINGS
Warning 1
Check with your doctor or pharmacist before taking your medicine if you have difficulty in breathing, wheezing, tightness in the chest (asthma) or an infection in your lungs (bronchitis).
Warning 2
Check with your doctor or pharmacist before taking your medicine if You have any serious heart problems .
Warning 3
Check with your doctor or pharmacist before taking your medicine if you have a stomach blockage or difficulty in passing water (urine).
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
Polyfax Eye Ointment 6g (Polymyxin B , Bacitracin) – GSK
Used For
Eye Infection
How it works
It contains the active ingredients polymyxin B sulphate and bacitracin zinc. Polymyxin B sulphate and bacitracin zinc are antibacterials.
Usage And Safety
Dosage
Adults & Children : Apply two or more times daily. OR As directed by your physician.
Side Effects
All medicines can cause allergic reactions, although serious allergic reactions are very rare.
Drug Interactions
Ask your physician or pharmacist for any drug interactions.
Indication
Styes , conjunctivitis , blepharitis and keratitis.
When not to Use
Do not use if you: • Are allergic (hypersensitive) to polymyxin B sulphate, bacitracin zinc, other similar antibiotics, or any of the other ingredients. An allergic reaction may include rash, itching, difficulty breathing or swelling of the face, lips, throat or tongue.
Warnings
Long-term use may cause an increased growth of micro-organisms (germs) that are not affected by this medicine, such as fungi, and this could lead to an infection.
Take special care if you have a kidney disorder .
Always use exactly as your doctor has told you. You should check with your doctor if you are unsure.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
Polyfax Skin Ointment 20g (Polymyxin B , Bacitracin) – GSK
**Used For**
Wound Care
### How It Works
Polyfax Skin Ointment contains two antibacterial agents, **Polymyxin B Sulphate** and **Bacitracin Zinc**, which work together to help prevent and control bacterial infections on the skin. These ingredients act by inhibiting the growth of susceptible bacteria, helping to protect damaged skin and support the natural healing process.
## Usage & Safety
### Dosage
**Adults & Children:** Apply a thin layer to the affected area two or more times daily, or as directed by your physician.
### Side Effects
Possible side effects may include:
* Sensitization or allergic skin reactions
* Nephrotoxicity (rare, particularly with excessive absorption)
### Drug Interactions
Inform your doctor or pharmacist if you are currently taking, or have recently taken, any medications, including over-the-counter medicines and herbal products.
### Indication
Indicated for the prevention of bacterial skin infections associated with:
* Minor burns
* Skin graft procedures
* Surgical wounds
* Minor cuts, scratches, and abrasions
### When Not to Use
Do not use this product if you are allergic to **Polymyxin B Sulphate**, **Bacitracin Zinc**, related antibiotics, or any other ingredient in the formulation. Signs of an allergic reaction may include rash, itching, swelling of the face or throat, or difficulty breathing.
### Precautions
Excessive absorption through large areas of damaged skin may increase the risk of nerve or kidney-related side effects. If extensive areas require treatment, your physician may monitor kidney function during therapy.
### Warning
Prolonged or repeated use may encourage the growth of microorganisms that are not affected by this ointment, including fungi, which may lead to secondary infections.
Consult your doctor before use in children requiring treatment over large skin areas.
Patients with kidney disorders should use this product with caution and seek medical advice before treatment.
## Additional Information
### Pregnancy Category
Always consult your physician before using any medication during pregnancy or breastfeeding.
### Storage
Store at room temperature in a cool, dry place away from direct sunlight, heat, and moisture. Keep out of the reach of children.
Pred Forte Eye Drop ( Prednisolone ) 5ml Barrett Hodgson Pakistan
Generics
Prednisolone
Used For
Eye Inflammation
How it works
It reduces the irritation, burning, redness and swelling of eye inflammation caused by chemicals, heat, radiation, allergy, or foreign objects in the eye.
Pred Forte Usage And Safety
Dosage
Prednisolone
Side Effects
*Allergic reaction * headache * increased pressure within the eye * centre of the eye becomes cloudy (cataracts) * A feeling that something is in your eye *Eye infections (bacterial, fungal or viral) * Mild stinging or irritation *Red eye *Blurred or poor vision * Pupil dilation * Change in sense of taste * Rash or itching
Drug Interactions
Ritonavir, cobicistat
Indication
It is used in adults for the short-term treatment of eye inflammation.
When not to Use
Do not use : If you are allergic to prednisolone acetate, benzalkonium chloride or any of the other ingredients of this medicine . - If you suffer from viral, fungal or bacterial eye infections . - If you suffer from tuberculosis of the eye.
Pred Forte Precautions
Precaution
It may cause temporary blurred vision. Do not drive or use machinery until the symptoms have cleared.
Pred Forte Warnings
Warning 1
Talk to your doctor before using if you suffer from, or have in the past suffered from Eye ulcers or have had a disease or treatment to the eye that caused the tissue to become thin.
Warning 2
This medicine contain Benzalkonium chloride . It may be absorbed by soft contact lenses and may change the colour of the contact lenses. You should remove contact lenses before using this medicine and put them back 15 minutes afterwards.
Warning 3
To avoid eye injury and contamination, do not let the tip of the dropper touch your eye or anything else.
Pred Forte Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
Prednicol Eye Drop 10ml (Anti-Infective) – Remington Pharmaceuticals
## **Usage & Safety**
### **Administration**
* Instill **1–2 drops** into the affected eye(s), **2–4 times daily**, or as directed by your physician.
* **Shake the bottle well** before each use to ensure proper suspension of the medication.
---
### **Duration of Use**
Prednicol Eye Drops are intended for **short-term treatment**. Prolonged use, especially for **more than one week**, should only be undertaken under the supervision of an ophthalmologist, as extended use may increase the risk of ocular complications.
---
### **Precautions**
* Do not discontinue the medication abruptly unless advised by your physician, as this may lead to a recurrence of inflammation.
* Avoid wearing **contact lenses** during treatment unless your eye care professional instructs otherwise.
* Store the product at **2°C–8°C (Refrigerated)**. **Do not freeze.**
* Do not use the solution if the bottle is damaged or if the suspension appears contaminated or discolored.
---
## **Possible Side Effects**
Prednicol Eye Drops are generally well tolerated; however, some patients may experience:
### **Common**
* Temporary burning or stinging sensation
* Mild eye irritation
* Transient blurred vision immediately after instillation
### **Less Common**
* Eye redness or discomfort
* Increased sensitivity to light
### **Serious (Associated with Prolonged Use)**
* Increased intraocular pressure (**glaucoma**)
* Cataract formation
* Delayed corneal or ocular wound healing
* Increased susceptibility to secondary eye infections
### **Rare**
* Chloramphenicol has been rarely associated with serious blood disorders, including **aplastic anemia**. Seek immediate medical attention if unusual bruising, persistent fever, sore throat, or unexplained fatigue occurs.
---
### **Important Safety Information**
Use this medicine only for the condition prescribed by your physician. If symptoms persist, worsen, or new symptoms develop, discontinue use and seek prompt medical advice.
Probeta-N Eye Ear And Nose Drops ( Betamethasone Sodium Phosphate , Neomycin ) 7.5Ml , Atco
Used For Eye Infection, Ear Infection , Nasal Congestion
It work by reducing inflammation (redness, itching and soreness). Topical means that they are used on the outside of the body and not taken by mouth or injection. It also contain neomycin sulphate, an aminoglycoside antibiotic, which prevents bacterial infection developing .
Usage And Safety
Dosage
Betamethasone Sodium Phosphate , Neomycin
Side Effects
Corneal thinning , cataract , rise in intra-ocular pressure , sensitization and cross resistance to neomycin ; avoid unnecessary use .
Drug Interactions
Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Indication
Eye : Non-infected inflammatory conditions (e.g . Uveitis , marginal keratitis , allergic conjunctivitis , blepharitis and episcleritis ) where development of bacterial infection is likely. Ear : Otitis externa and other inflammatory conditions where bacterial infection is present or suspected. Nose : Inflammatory conditions where infection is present or suspected .
When not to Use
Do not use if allergic to any of the ingredients in the list.
Precautions
Precaution
Do not use if you know you have (or think you have) a mitochondrial disease (mutations in the parts of your cells which help make energy); certain mitochondrial diseases may increase your risk of hearing loss with this product.
Warnings
Warning 1
Talk to your doctor or pharmacist before using this medicine if you have been treated with these drops/ointment or similar corticosteroid medicine recently. You should not use corticosteroids for a long time without regular medical check-ups from your doctor .
Warning 2
Talk to your doctor or pharmacist before using this medicine if you have redness in your eyes for which you do not know the cause. Steroid treatment must not be given unless the cause of the redness is known .
Warning 3
Talk to your doctor or pharmacist before using this medicine if you are applying these drops to open wounds or damaged skin. The antibiotic component can cause permanent, partial or total deafness if used on open wounds or damaged skin. This possibility should be borne in mind if high doses are given to small children or infants.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
Progel Antacid 120ml Syrup – Alpha
**How It Works**
This medicine helps relieve heartburn and excess gastric acidity by neutralizing stomach acid, providing fast and effective relief from acid-related discomfort.
**Ingredients**
Antacid
**Drug Class**
Antacid
**Dosage Form**
Syrup / Suspension
**Uses**
This medicine is commonly used for the management of:
* Dyspepsia (indigestion)
* Reflux esophagitis
* Heartburn
* Hiatus hernia
**Dosage**
Use this medicine exactly as prescribed by your doctor.
**Overdose**
An overdose may lead to serious health complications and can be life-threatening in some cases. Seek immediate medical attention if an overdose is suspected.
**Missed Dose**
If you forget to take a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
**How To Use**
For best results, it is generally recommended to take this medicine after meals.
**When Not to Use**
Do not use this medicine if you are allergic to any of its ingredients.
**Side Effects**
Like all medicines, this product may cause side effects in some individuals. Consult your healthcare provider if any unwanted effects occur or persist.
**Precautions & Warnings**
Pregnant or breastfeeding women should consult their doctor before using this medicine.
**Drug Interactions**
No significant drug interactions have been reported to date.
**Storage & Disposal**
Store in a cool, dry place away from direct sunlight and moisture. Keep out of the reach of children and ensure the container remains tightly closed after use.
R-D Tar Medicated Soap ( Royal Derma )
Rifaxa 550mg Tab ( Rifaximin ) Ferozsons
Rifaximin is used to treat travelers' diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old. Most people get this infection by eating food or drinking fluids that have been contaminated with the E. coli bacteria.
Rifaximin is also used to treat irritable bowel syndrome (IBS) in adults whose main symptom is diarrhea.
Rifaximin is also used to lower the risk of a decline in brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.
Rifaximin may also be used for purposes not listed in this medication guide.
Rifaximin side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Rifaximin may cause serious side effects. Call your doctor at once if you have:
severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
fever; or
fluid build-up around the stomach--rapid weight gain, stomach pain and bloating, trouble breathing while lying down.
Common side effects of rifaximin may include:
swelling in your hands or feet;
nausea;
headache, dizziness;
tiredness; or
abnormal liver function tests.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not take rifaximin if you are allergic to rifaximin, rifabutin, rifampin, or rifapentine.
Tell your doctor if you have ever had:
liver disease;
diarrhea with a fever; or
watery or bloody diarrhea.
Tell your doctor if you are pregnant or breastfeeding.
Rifaximin should not be given to a child younger than 12 years old.
How should I take rifaximin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take rifaximin with or without food.
For travelers' diarrhea, rifaximin is usually taken for only 3 days. For IBS, rifaximin is usually taken for 2 weeks at a time. Follow your doctor's dosing instructions very carefully.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Rifaximin will not treat a viral infection such as the flu or a common cold.
Do not share this medicine with another person, even if they have the same symptoms you have.
Call your doctor if your symptoms do not improve after 24 to 48 hours, or if they get worse while using rifaximin.
Rifaximin does not treat all bacterial forms of travelers' diarrhea.
Store at room temperature away from moisture and heat.
Rifaximin dosing information
Usual Adult Dose for Traveler's Diarrhea:
200 mg orally 3 times a day for 3 days
Comments:
-This drug should not be used in patients with diarrhea complicated by fever or blood in the stool or diarrhea caused by pathogens other than Escherichia coli.
Use: For the treatment of travelers' diarrhea due to noninvasive strains of E coli
Usual Adult Dose for Hepatic Encephalopathy:
550 mg orally twice a day
Comments:
-In trials, lactulose was used concomitantly in 91% of patients; differences in treatment effect of patients not using concomitant lactulose could not be assessed.
Use: For reduction in risk of overt hepatic encephalopathy recurrence
Usual Adult Dose for Irritable Bowel Syndrome:
550 mg orally 3 times a day for 14 days
Comments:
-If symptoms recur, patients can be retreated up to 2 times with the same dosage regimen.
Use: For the treatment of irritable bowel syndrome with diarrhea
Usual Pediatric Dose for Traveler's Diarrhea:
12 years or older: 200 mg orally 3 times a day for 3 days
-This drug should not be used in patients with diarrhea complicated by fever or blood in the stool or diarrhea caused by pathogens other than E coli.
Royal Derma ( Prickly Heat Soap ) Royal Derma
Sacvin Tablets 24mg/26mg (Sacubitril , Valsartan) PharmEvo
Used For
Heart FailureHow it works
Sacubitril + valsartan inhibits neprilysin (neutral endopeptidase; NEP) , the active metabolite of the prodrug sacubitril and blocks the angiotensin II type-1 (AT1) receptor via valsartan. The cardiovascular and renal effects of sacubitril + valsartan in heart failure patients are attributed to the increased levels of peptides that are degraded by neprilysin, such as natriuretic peptides (NPs) and the simultaneous inhibition of the effects of angiotensin II by valsartan. NPs exert their effects by activating membrane bound guanylyl cyclase coupled receptors, resulting in increased concentrations of the second messenger cyclic guanosine monophosphate (cGMP), which could result in vasodilation, natriuresis and diuresis, increased glomerular filtration rate and renal blood flow, inhibition of renin and aldosterone release, reduction ofsympathetic activity and antihypertrophic and antifibrotic effects. Valsartan inhibits the effects of angiotensin II by selectively blocking the AT1 receptor and also inhibits angiotensin II-dependent aldosterone release. This prevents sustained activation of the renin-angiotensin-aldosterone system that would result in vasoconstriction, renal sodium and fluid retention, activation of cellular growth and proliferation and subsequent maladaptive cardiovascular remodeling.Usage And Safety
Dosage
The recommended starting dose of Sacubitril + Valsartan is one tablet of 49mg + 51mg twice daily.The dose of Sacubitril + Valsartan should be doubled after 2 to 4 weeks to the target maintenance dose of one tablet of 97mg + 103mg twice daily, as tolerated by the patient. Starting dose for some populations : A starting dose of (Sacubitril + Valsartan) one tablet of 24mg + 26mg taken twice daily is recommended for patients not currently taking an ACE inhibitor or an ARB or patients previously taking low doses of these agents. A starting dose of Sacubitril + Valsartan of one tablet of 24mg + 26mg taken twice daily should be considered for patients who have risk factors for hypotension, including patients = 75 years old and patients with low systolic blood pressure (SBP =100 to 110 mmHg). The dose of Sacubitril + Valsartan should be doubled every 2-4 weeks to the target dose of one tablet of Sacubitril + Valsartan 97mg + 103 mg twice daily, as tolerated by the patient. Always consult your doctor or pharmacist for dose adjustments.Side Effects
Very Common : Hyperkalemia, hypotension and renal impairment.Common : Anemia, hypokalemia, hypoglycemia, dizziness, headache, syncope, vertigo, orthostatic hypotension, cough, diarrhea, nausea, gastritis, renal failure (renal failure, acute renal failure), fatigue and asthenia.Uncommon : Hypersensitivity, dizziness postural, pruritus, rash and angioedema.Drug Interactions
Angiotensin Receptor Blockers , OATP1B1 and OATP1B3 substrates, e.g. statins , PDE5 inhibitors including sildenafil , potassium-sparing diuretics (triamterene, amiloride), mineralocorticoid antagonists (e.g. spironolactone, eplerenone), potassium supplements, salt substitutes containing potassium or other agents (such as heparin) , Non-steroidal anti-inflammatory agents (NSAIDs), including selective cyclooxygenase-2 (COX-2) inhibitors , Lithium , OATP1B1, OATP1B3, OAT3 (e.g. rifampicin, ciclosporin), OAT1 (e.g. tenofovir, cidofovir) or MRP2 (e.g. ritonavir) , Metformin HCl.Indication
Sacubitril + Valsartan is indicated in adult patients for treatment of symptomatic chronic heart failure with reduced ejection fraction. Sacubitril + Valsartan is usually administered in conjunction with other heart failure therapies, in place of an ACE inhibitor or other ARB.When not to Use
Sacubitril + Valsartan is contraindicated in patients with:• Hypersensitivity to the active substance, sacubitril, valsartan or to any of the excipient of the product.• Concomitant use with ACE inhibitors. Sacubitril + Valsartan must not be administered until 36 hours after discontinuing ACE inhibitor therapy.• Known history of angioedema related to previous ACE inhibitor or ARB therapy.• Hereditary or idiopathic angioedema.• Concomitant use with aliskiren-containing medicinal products in patients with diabetes mellitus or in patients with renal impairment (eGFR <60 ml/min/1.73 m2 ).• Severe hepatic impairment, biliary cirrhosis and cholestasis.• Second and third trimester of pregnancyPrecautions
Sacubitril + valsartan may cause angioedema. If angioedema occurs, discontinue sacubitril + valsartan immediately, provide appropriate therapy and monitor for airway compromise. Sacubitril + valsartan should not be used in patients with a known history of angioedema related to previous ACE inhibitor or ARB therapy.
Warnings
- ) Sacubitril + valsartan lowers blood pressure and may cause symptomatic hypotension. Patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), are at greater risk. Correct volume or salt depletion prior to administration of sacubitril + valsartan or start at a lower dose. If hypotension occurs, consider dose adjustment of diuretics, concomitant antihypertensive drugs and treatment of other causes of hypotension (e.g., hypovolemia). If hypotension persists despite such measures, reduce the dosage or temporarily discontinue sacubitril + valsartan.
- ) Through its actions on the RAAS, hyperkalemia may occur with sacubitril + valsartan. Monitor serum potassium periodically and treat appropriately, especially in patients with risk factors for hyperkalemia such as severe renal impairment, diabetes, hypoaldosteronism or a high potassium diet. Dosage reduction or interruption of sacubitril + valsartan may be required.
3. ) Caution should be exercised when initiating sacubitril + valsartan in patients with NYHA functional classification IV due to limited clinical experience in this population.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
Salysul Medicated Soap, For Oily Skin & Fungal Infection, 100g Royal Derma
SALYSUL Soap is extremely effective in excessive oily skin, seborrhea and tinea Versicolor it contains 3.5% Precipitated sulfur & 1 % Salicylic acid approx. avoid patients sensitive to sulfur contact with eyes or mucous membranes should be avoided
How to use: wash with normal or lukewarm water and then apply the soap message it gently until rich lather is formed then rinse with water