Inosita Plus 50/1000mg Tab. ( Sitagliptin, Metformin ) Pharmevo
Generics : Sitagliptin, Metformin
Used For
Diabetes
How it works
By increasing and prolonging active incretin levels, Sitagliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner. It is a biguanide with antihyperglycemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycemia.
Inosita Plus Usage And Safety
Dosage
Sitagliptin, Metformin
Side Effects
Common: nausea.Uncommon: somnolence, diarrhea, upper abdominal pain and blood glucose decreased.
Drug Interactions
Digoxin , Furosemide , Nifedipine , Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine ranitidine, triamterene, trimethoprim, or vancomycin) , thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid.
Indication
It is indicated as: - Initial therapy in patients with type 2 diabetes mellitus to improve glycemic control when diet and exercise do not provide adequate glycemic control. As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus inadequately controlled on Metformin HCl or Sitagliptin alone or in patients already being treated with the combination of Sitagliptin and Metformin HCl.
When not to Use
The combination of Sitagliptin and Metformin HCl is contraindicated in:- Patients with type 1 diabetes. -Patients with known hypersensitivity to Sitagliptin, Metformin HCl or any other component of the product. - Acute or chronic metabolic acidosis , including ketoacidosis, with or without coma.
Inosita Plus Precautions
Precaution
Sitagliptin+Metformin HCl are known to be substantially excreted by the kidney.Metformin HCl-related lactic acidosis increases with the degree of insufficiency of renal function, therefore, serum creatinine concentrations should be determined regularly.
Inosita Plus Warnings
Warning 1
Since impaired hepatic function has been associated with some cases of lactic acidosis, Sitagliptin+Metformin HCl should generally be avoided in patients with clinical or laboratory evidence of hepatic disease.
Warning 2
Patient receiving Sitagliptin+Metformin HCl in combination with a sulphonylurea or with insulin may be at risk for hypoglycemia. Therefore, a reduction in the dose of the sulphonylurea or insulin may be necessary.
Warning 3
After initiation of Sitagliptin, patients should be observed carefully for signs and symptoms of pancreatitis. If pancreatitis is suspected, Sitagliptin should promptly be discontinued and appropriate management should be initiated.
Inosita Plus Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
And Also Available on 50/500
Inosita Plus XR (50/1000mg)
Instant Enema 120ml (Saline Laxative) – ISIS
# **Instant Enema 120 ml**
## **Active Ingredients**
Instant Enema contains **Sodium Phosphates** (including **Dibasic Sodium Phosphate** and **Monobasic Sodium Phosphate**), which act as saline laxatives. These ingredients work by drawing water into the bowel, softening stool and stimulating rapid bowel evacuation.
---
## **Packaging**
Instant Enema is supplied in a **120 ml ready-to-use squeeze bottle**. The bottle is designed with:
* A soft, flexible applicator tip for comfortable insertion.
* A one-way safety valve that helps prevent reflux and maintains hygienic administration.
---
## **How It Works**
The saline formulation increases the water content in the lower bowel, promoting a quick and effective bowel movement. Relief is typically experienced within **1–5 minutes** after administration.
---
## **Indications**
Instant Enema is indicated for:
* Relief of **occasional constipation**.
* Cleansing of the bowel prior to diagnostic or surgical procedures, including **colonoscopy** and other medical examinations, as directed by a healthcare professional.
---
## **Dosage & Administration**
### **Recommended Dosage**
**Adults:** Use **one 120 ml bottle once daily**, or as directed by your physician.
### **Administration**
* **For rectal use only.**
* The product should be administered while lying on the **left side with both knees slightly bent**, unless otherwise instructed by a healthcare professional.
* Use only as directed. Do not exceed the recommended dosage.
---
## **Warnings & Precautions**
* Do not use if you have **severe abdominal pain, nausea, vomiting, intestinal obstruction, acute gastrointestinal disorders, congestive heart failure, or severe kidney disease**, unless advised by your physician.
* Avoid prolonged or frequent use, as excessive use may result in dehydration, electrolyte imbalance, or dependence on laxatives.
* If constipation persists after use or symptoms worsen, discontinue use and consult your healthcare provider.
* Keep out of the reach of children.
---
## **Possible Side Effects**
Most users tolerate Instant Enema well; however, some may experience:
* Mild abdominal discomfort or cramping
* Temporary rectal irritation
* Gas or bloating
In rare cases, repeated or excessive use may lead to **electrolyte disturbances** or **laxative dependence**. Seek medical advice if severe or persistent side effects occur.
---
## **Age Restriction**
Instant Enema is **not generally recommended for children under 2 years of age** unless specifically prescribed by a physician.
---
## **Storage Instructions**
Store in a cool, dry place at room temperature, away from direct sunlight and excessive heat. Do not freeze. Keep the bottle tightly closed until ready for use.
Itrazox 100mg ( Itraconazole ) Maxitech
Itraconazole Used For Fungal Infection
Itraconazole is used to treat yeast infections of the mouth and throat or of the esophagus (tube that connects the throat to the stomach). Itraconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection.
Itrazox Capsules Usage And Safety
Dosage
Itraconazole
Side Effects
Granulocytopenia, Thrombocytopenia , Hyperglycemia, Hyperkalemia, Hypokalemia, Hypomagnesemia , Confusional state , Neuropathy peripheral, Dizziness, Somnolence , Cardiac failure, Left ventricular failure, Tachycardia , : Hypertension, Hypotension , Gastrointestinal disorder , Hepatic failure, Hepatitis, Jaundice , Rash erythematous, Hyperhidrosis , Myalgia, Arthralgia , : Generalized edema, Face edema, Chest pain, Pyrexia, Pain, Fatigue, Chills .
Drug Interactions
Itraconazole : Rifampicin , cyclosporin , H2 antagonists , antacids , tamsulosin , antiarrhythmics , digoxin , cilosrazole , repaglinide , saxagliptin , midazolam , nadolol , tacrolimus , salmeterol , reboxetine , statins , tolvaptan , meloxicam , sirolimus , domperidone , ivabradine, ergot alkaloids.
Indication
It is used for infections caused by fungi or yeasts such as vaginal infections, dermatological infections, onychomycosis etc.
When not to Use
It is contraindicated in patients with known hypersensitivity to itraconazole or to any of the excipients.
Itrazox Capsules Precautions
Precaution
When driving vehicles and operating machinery the possibility of adverse reactions such as dizziness, visual disturbances and hearing loss , which may occur in some instances, must be taken into account.
Itrazox Capsules Warnings
Warning 1
Itraconazole has been shown to have a negative inotropic effect and it has been associated with reports of CHF.
Warning 2
There is limited information regarding cross-hypersensitivity between itraconazole and other azole antifungal agents. Caution should be used in prescribing itraconazole capsules to patients with hypersensitivity to other azoles.
Warning 3
The use of capsules in pediatric patients is not recommended unless it is determined that the potential benefit outweighs the potential risks.
Itrazox Capsules Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
IZMEPRA 40MG CAP (Omeprazole 40mg) – EPHARM LABORATORIES
# **Izmepra Capsules (Esomeprazole)**
## **Common Uses**
Izmepra contains **Esomeprazole**, a proton pump inhibitor (PPI) that reduces the production of stomach acid. It is used in the treatment and management of various acid-related gastrointestinal disorders, including:
* **Gastroesophageal Reflux Disease (GERD):** Relieves symptoms such as heartburn and acid reflux while promoting the healing of erosive esophagitis.
* **Gastric and Duodenal Ulcers:** Used for the treatment and prevention of ulcers, including those associated with *Helicobacter pylori* infection (in combination with appropriate antibiotics) and ulcers caused by prolonged NSAID use.
* **Zollinger-Ellison Syndrome:** Helps control excessive gastric acid secretion in patients with this rare condition.
---
## **How It Works**
Esomeprazole works by blocking the **proton pumps** in the stomach lining that produce acid. By reducing acid secretion, it allows ulcers to heal, relieves reflux symptoms, and helps prevent further damage to the esophagus and stomach.
---
## **Usage & Safety**
### **Administration**
* Take the capsule **exactly as prescribed** by your physician.
* Swallow the capsule **whole with water**.
* Do **not** crush, chew, or open the capsule, as this may affect its effectiveness.
* For optimal results, it is generally recommended to take the medicine **before a meal**, preferably in the morning.
---
## **Possible Side Effects**
Izmepra is generally well tolerated. However, some individuals may experience:
* Headache
* Abdominal pain
* Diarrhea
* Constipation
* Nausea
* Flatulence
These side effects are usually mild and temporary. Consult your physician if they persist or become troublesome.
---
## **Warnings & Precautions**
* Long-term use (particularly **longer than 3 months**) may increase the risk of **low magnesium levels**, **Vitamin B12 deficiency**, and **bone fractures** in some patients.
* Inform your physician if you have liver disease, osteoporosis, or are taking other long-term medications.
* Seek immediate medical attention if you develop signs of an allergic reaction, including **difficulty breathing, swelling of the face, lips, tongue, or throat, or severe skin rash**.
* Use only under the supervision of a qualified healthcare professional.
---
## **Storage Instructions**
Store below **30°C** in a cool, dry place, away from direct sunlight and moisture. Keep out of the reach of children.
JARDIN D SYRUP ( Desloratadine ) HIGH-Q
Jardin-D Syrup 120ml formula
Desloratadine
Available forms
Syrup
Tablets
Risks and warnings
You should know the risks and warnings of Jardin-D syrup to prevent its misuse.
There are some specific circumstances under which the use of certain medications is contraindicated or considered dangerous. So when taking any medicine, it's always a good practice to familiarize yourself with its risks and warnings.
The risks and warnings associated with Jardin-D syrup are:
Pregnancy and Lactation
Pregnant and lactating women should only use this medicine after consultation with their doctor.
Liver and Kidney diseases
People with liver and renal impairment should consult their doctor before using this medicine.
Diabetes and infections
When treating patients with infections or diabetes, desloratadine should be administered with utmost caution.
Allergic reactions
Before taking desloratadine, patients who are allergic to it or any of its ingredients should speak with a doctor.
Driving
Driving and alcohol should be avoided while taking this medicine as it can make you dizzy or cause drowsiness.
Alcohol
Avoid intake of alcohol while taking Jardin D.
Vitamins and nutritional supplements
Before taking desloratadine, visit a doctor if you're taking any vitamins, nutritional supplements, or herbal remedies.
How to use Jardin-D Syrup 120ml?
Shake well before use
Take the syrup orally with or without food as prescribed by your doctor.
Use a measuring cup, spoon or a dropper for the right quantity
To obtain the best benefit from desloratadine, take it regularly.
Your medical condition and treatment response will determine the quantity
Do not take this medication in larger amounts or more frequently than recommended.
Jardin-D Syrup Side Effects
Some common side effects of Jardin-D Syrup include:
Nausea
Vomiting
Sore throat
Tiredness
Upset stomach
Muscle pain
Fever
Diarrhea
Dizziness
Trouble sleeping
Appetite changes
Rash
Itching/swelling
Drug Interactions
Jardin-D can interact with the following drugs:
Fruit juices (e.g. grapefruit, apple, orange juice)
CNS depressants
Azole antifungals
Macrolide antibiotics
Cimetidine
Storage Conditions
Store the medicine at room temperature
Keep out of reach and sight of children
Protect it from light and moisture
Jardin D Tablet ( Desloratadine ) HIGH-Q
- Take desloratadine by mouth with or without food as directed by your doctor.
- Take the exact quantity of desloratadine as prescribed by the doctor.
- If you are using the rapidly-dissolving tablet, allow the tablet to dissolve on the tongue and then swallow.
- Do not remove the tablet from the blister pack until right before using.
- If you are using the liquid form of desloratadine, carefully measure the dose using a special measuring device/spoon.
- Do not use a household spoon because you may not get the correct dose.
- Take desloratadine regularly to get the most benefit from it.
- To help remember, take desloratadine at the same time.
- Quantity is based on your medical condition and response to treatment.
- Do not increase your quantity or take this product more often than directed.
Expert Advice
Do not increase the quantity than prescribed by the doctor. If the condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away. Do not flush desloratadine down the toilet. Keep desloratadine out of the reach of children. Store the desloratadine at room temperature. Keep desloratadine away from sunlight.Primary Uses
AllergyIndications
- Desloratadine is indicated for the treatment of allergic reactions.
- Desloratadine is safe and effective in reducing infections.
Side Effects
Side effects of desloratadine include:- Nausea
- Vomiting
- Sore throat
- Tiredness
- Stomach upset
- Muscle pain
- Fever
- Diarrhea
- Dizziness
- Trouble sleeping
- Appetite changes
- Rash
- Itching/swelling.
Warnings
PregnancyConsult your doctor before using desloratadine during pregnancy for a better analysis.
LactationConsult your doctor before using desloratadine during lactation for a better analysis.
DrivingIts use has shown a risk of drowsiness; therefore avoid using it while driving.
LiverIts use has shown risk to the liver. Consult your doctor before using desloratadine for a better analysis
KidneyIts use has shown risk to kidneys. Consult your doctor before using desloratadine for a better analysis.
AlcoholThe use of alcohol shoule be avoided while using this medicine.
PrecautionsPatients who are allergic to desloratadine or any of its components should consult the doctor before taking it. If taking any vitamins, nutritional supplements, and herbal products are taken then consult the doctor before using desloratadine. If any sort of swelling is experienced, consult your doctor immediately. Using desloratadine, especially in high concentrations, might result in stomach upset.
Contraindications
- Desloratadine is contraindicated for use in patients with desloratadine
- Desloratadine should be used with extreme caution in patients with infections.
- Desloratadine should be used with extreme caution in patients with diabetes.
FAQS
What are the uses of Desloratadine?This medication is used for treating symptoms of allergy such as runny nose, watery eyes, itchy eyes/nose/throat, sneezing, rash, etc.How to store Desloratadine?Please store this medicine at room temperature (18-25 Celsius). Keep medicine away from excessive light, moisture, and children. Please do not flush medicines down the toilet. Please read the leaflet provided with the medicine for further storage guidance.What are the side effects of taking Desloratadine?You may experience the following: • Changes in appetite • Trouble sleepingWhat are the precautions for taking Desloratadine?Following are the precautions for use of this medicine: • Do not use or discontinue this medicine if you are allergic to any of the ingredients of this medicine • You may feel drowsy after taking this medicine therefore avoid doing work requiring alertness (e.g. driving) after taking this medicineDoes Desloratadine have any effect on pregnancy and lactation?This medicine should only be used during pregnancy if no safer alternate is available. Consult your health care provider for guidance. This medicine is contraindicated for lactating females. Consult your health care provider for guidance.How to use this medicine?This medicine is mostly taken through the mouth. The dose is dependent on the age, condition and its severity.
kemadrin 5mg tablet ( Procyclidine ) GSK
If you are taking this medication for side effects from another medication, your doctor may instruct you to take it on a regular schedule or only as needed. If you are taking this medication for Parkinson's disease, your doctor may change the dose of your other medications (such as levodopa). Follow your doctor's instructions closely. Do not stop or change the dose of your medication without your doctor's approval.
Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.
When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.
Tell your doctor if your condition lasts or gets worse.
Kenacomb Cream – GSK
KENACOMB combines the potent corticosteroid triamcinolone acetonide with the antifungal antibiotic nystatin and the wide spectrum antibacterial activity of neomycin and gramicidin.
KENACOMB reduces inflammation, relieves pruritis and combats or prevents monilial and bacterial infections.
Pharmacokinetics
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin increase percutaneous absorption.
Nystatin and gramicidin are not absorbed from intact skin or mucous membranes.
Neomycin can be absorbed through inflamed skin. Once absorbed, it is rapidly excreted unchanged through the kidneys. The half-life is approximately 2 to 3 hours.
Microbiology
Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components.
Nystatin exhibits no activity against bacteria, protozoa, or viruses.
Neomycin exerts its bacterial activity against a number of gram-negative organisms by inhibiting protein synthesis. It is not active against Pseudomonas aeruginosa, and resistant strains of gram-negative bacteria may develop.
Gramicidin exerts its antibacterial activity against many gram-positive organisms by altering cell membrane permeability.
INDICATIONS
KENACOMB is indicated for use in corticosteroid responsive dermatoses complicated or threatened by secondary monilial and/or bacterial infections, such as:
Atopic dermatitis
Seborrhoeic dermatitis
Lichen simplex chronicus
Psoriasis (particularly of the face and body folds)
Allergic contact dermatitis
KENACOMB CREAM permits use in moist intertrigenous areas.
Kenalog Ointment (Triamcinolone Acetonide) – gsk
Kenalog is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Triamcinolone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a medium- to strong-potency corticosteroid. The potency depends on the strength and the form that you use. For details on the potency of your product, ask your pharmacist.
Ketosteril Tablet ( Ketoanalogues + Essential Amino Acids ) fresenius kabi
Ketosteril is used to prevent and preserve patients with chronic renal failure with a glomerular filtration rate of 5-15 ml/min. The drug is used in combination with a restricted protein diet (protein intake 40g per day in adults or less)
The drug helps to relieve symptoms caused by uremia, reduce proteinuria, prevent protein breakdown of the body, correcting disorders of calcium-phosphate metabolism, hyperparathyroidism and renal osteoporosis, helping to improve carbohydrate metabolism disorders, lipid metabolism, and endocrine disorders.
Ketosteril allows the body to take in essential amino acids while minimizing nitrogen-nitrogen intake. Once absorbed into the body, the keto- and hydroxy analogues will be converted to essential amino acids by taking nitrogen from the non-essential amino acids, thereby reducing urea formation by using amine group.
Therefore, the accumulation of uraemia toxins is reduced. Keto and hydroxy acids do not induce ultrafiltration in the remaining nephrons. Ketosteril contains a supplement that promotes a positive effect on renal hyperphosphatemia and secondary hyperparathyroidism.
Furthermore, renal osteodystrophy may be improved with the use of Ketosteril. The use of Ketosteril in combination with a very low protein diet reduces nitrogen intake to prevent serious consequences of protein supplementation in patients with renal failure.
How to use Ketosteril:
Use Ketosteril as prescribed by your doctor. Do not arbitrarily increase, decrease the dose or prolong the time of using Ketosteril compared to the indicated. Take Ketosteril tablets with food, do not chew the medicine. During the use of Ketosteril drug, it is necessary to monitor the amount of protein taken into the body. Before dialysis, protein intake should not exceed 40g/day for adults; for children from 3-10 years old: 1.4-0.8g/kg; for children 10 years and older: 1-0.6g/kg.. You should consult your doctor during dialysis.
Kleen Enema ( Sodium Biphosphate , Sodium Phosphate ) Nabiqasim Industries
This medication is indicated in patients with constipation and bowel clearence.
Pregnancy:
During pregnancy this medication should only be used when clearly needed. Consult your doctor before using this medication.
Lactation:
No definite data regarding lactating females is available, therefore; be cautious. Consult your doctor before using this medication.
Contraindications:
This medication is contraindicated in patients with acute GI conditions, GI obstruction, abdominal pain, nausea, vomiting, renal (kidney) failure, congestive heart failure.
Precautions:
Elderly and weak patients. restricted sodium intake, renal (kidney) impairment, heart disease and colostomy (surgical procedure).
Adverse effects:
Patients administered with this medication may experience mild abdominal discomfort or gas may occur.
Primary Uses
Constipation
Indications
This medication is indicated in patients with constipation and bowel clearence.
Side Effects
Patients administered with this medication may experience mild abdominal discomfort or gas may occur.
Warnings
Pregnancy
During pregnancy this medication should only be used when clearly needed. Consult your doctor before using this medication.
Lactation
No definite data regarding lactating females is available, therefore; be cautious. Consult your doctor before using this medication.
Driving
Please avoid driving when taking this medicine as it may affect your ability to drive.
Precautions
Elderly and weak patients. restricted sodium intake, renal (kidney) impairment, heart disease and colostomy (surgical procedure).
Contraindications
This medication is contraindicated in patients with acute GI conditions, GI obstruction, abdominal pain, nausea, vomiting, renal (kidney) failure, congestive heart failure.
FAQS
Uses:
This medication is used for treating severe constipation. It helps soften stools and increases the number of bowel movements, making passing stools easier. It can also be used to clean the intestines before and surgery or medical procedure. This medicine is not recommended for children less than two years of age.
Storage:
Please read the leaflet provided with the medicine for storage guidance. Keep medicine away from excessive light, moisture, and children. Please do not flush medicines down the toilet.
Side Effects:
You may experience the following: • Gas • Abdominal discomfort
Precautions:
Following are the precautions for using this medicine: • You may develop dependency therefore use Enema Liquid only when absolutely necessary • Drink plenty of water to prevent dehydration • Children may be more sensitive to the side effects
Will I see instant results?
It may take up to 30 minutes for this medicine to work effectively.
Effects on pregnancy and lactation:
This medicine should only be used during pregnancy if no safer alternate is available. The effects of this medicine on lactating females are unknown. Consult your health care provider before use of this medicine.