Abhayrab Rabies Vaccine (Purified Vero Cell Rabies Vaccine) – Human Biologicals Institute

Used For

Abhayrab is a purified Vero cell rabies vaccine used for the prevention of rabies. It may be used for post-exposure prophylaxis following possible exposure to rabies and for pre-exposure prophylaxis in individuals at increased risk of exposure.

How It Works

Abhayrab contains inactivated rabies virus antigen. After administration, it stimulates the immune system to produce protective antibodies against the rabies virus, helping prevent the development of rabies following exposure.

Usage & Safety

Dosage:
The dose and vaccination schedule depend on whether the vaccine is being used for pre-exposure or post-exposure prophylaxis, as well as the individual’s previous vaccination history. It should be administered by a qualified healthcare professional according to the recommended rabies vaccination schedule.

Side Effects:
Possible side effects may include pain, redness or swelling at the injection site, headache, fatigue, mild fever, muscle aches, or nausea. Serious allergic reactions are uncommon but require immediate medical attention.

Drug Interactions:
Medicines that suppress the immune system may reduce the immune response to the vaccine. Inform the healthcare professional about all medicines and vaccines being used.

Indications

• Post-exposure prophylaxis following potential exposure to rabies.
• Pre-exposure prophylaxis for individuals at increased risk of rabies exposure.
• Prevention of rabies infection according to recommended vaccination protocols.

When Not to Use

Do not use in individuals with a known severe allergic reaction to a previous dose of rabies vaccine or any component of the vaccine. For post-exposure treatment, vaccination should generally not be withheld solely because of a history of allergy; appropriate medical assessment is required.

Precautions

• Should be administered by a qualified healthcare professional.
• Follow the recommended vaccination schedule carefully.
• Seek immediate medical attention after any suspected rabies exposure.
• Individuals with weakened immune systems may require special medical consideration.
• The vaccine should be stored and handled according to the manufacturer’s requirements.

Warnings

Rabies is a potentially fatal disease. Following a suspected exposure, medical attention should be sought immediately. Depending on the exposure category and vaccination history, rabies immunoglobulin and a complete vaccine schedule may also be required. Abhayrab should not be self-administered.

Pregnancy

Rabies exposure can be life-threatening, and pregnancy is generally not considered a reason to withhold post-exposure rabies vaccination when indicated. Use during pregnancy should be determined by a healthcare professional based on the individual’s risk and clinical circumstances.

Storage

Store according to the manufacturer’s recommended conditions, generally under refrigerated conditions. Do not freeze. Protect from inappropriate temperatures and keep out of reach of children. Always check the product packaging for specific storage requirements.