Inosita Plus 50/1000mg Tab. ( Sitagliptin, Metformin ) Pharmevo
Generics : Sitagliptin, Metformin
Used For
Diabetes
How it works
By increasing and prolonging active incretin levels, Sitagliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner. It is a biguanide with antihyperglycemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycemia.
Inosita Plus Usage And Safety
Dosage
Sitagliptin, Metformin
Side Effects
Common: nausea.Uncommon: somnolence, diarrhea, upper abdominal pain and blood glucose decreased.
Drug Interactions
Digoxin , Furosemide , Nifedipine , Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine ranitidine, triamterene, trimethoprim, or vancomycin) , thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid.
Indication
It is indicated as: - Initial therapy in patients with type 2 diabetes mellitus to improve glycemic control when diet and exercise do not provide adequate glycemic control. As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus inadequately controlled on Metformin HCl or Sitagliptin alone or in patients already being treated with the combination of Sitagliptin and Metformin HCl.
When not to Use
The combination of Sitagliptin and Metformin HCl is contraindicated in:- Patients with type 1 diabetes. -Patients with known hypersensitivity to Sitagliptin, Metformin HCl or any other component of the product. - Acute or chronic metabolic acidosis , including ketoacidosis, with or without coma.
Inosita Plus Precautions
Precaution
Sitagliptin+Metformin HCl are known to be substantially excreted by the kidney.Metformin HCl-related lactic acidosis increases with the degree of insufficiency of renal function, therefore, serum creatinine concentrations should be determined regularly.
Inosita Plus Warnings
Warning 1
Since impaired hepatic function has been associated with some cases of lactic acidosis, Sitagliptin+Metformin HCl should generally be avoided in patients with clinical or laboratory evidence of hepatic disease.
Warning 2
Patient receiving Sitagliptin+Metformin HCl in combination with a sulphonylurea or with insulin may be at risk for hypoglycemia. Therefore, a reduction in the dose of the sulphonylurea or insulin may be necessary.
Warning 3
After initiation of Sitagliptin, patients should be observed carefully for signs and symptoms of pancreatitis. If pancreatitis is suspected, Sitagliptin should promptly be discontinued and appropriate management should be initiated.
Inosita Plus Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
And Also Available on 50/500
Inosita Plus XR (50/1000mg)
Instant Enema 120ml (Saline Laxative) – ISIS
# **Instant Enema 120 ml**
## **Active Ingredients**
Instant Enema contains **Sodium Phosphates** (including **Dibasic Sodium Phosphate** and **Monobasic Sodium Phosphate**), which act as saline laxatives. These ingredients work by drawing water into the bowel, softening stool and stimulating rapid bowel evacuation.
---
## **Packaging**
Instant Enema is supplied in a **120 ml ready-to-use squeeze bottle**. The bottle is designed with:
* A soft, flexible applicator tip for comfortable insertion.
* A one-way safety valve that helps prevent reflux and maintains hygienic administration.
---
## **How It Works**
The saline formulation increases the water content in the lower bowel, promoting a quick and effective bowel movement. Relief is typically experienced within **1–5 minutes** after administration.
---
## **Indications**
Instant Enema is indicated for:
* Relief of **occasional constipation**.
* Cleansing of the bowel prior to diagnostic or surgical procedures, including **colonoscopy** and other medical examinations, as directed by a healthcare professional.
---
## **Dosage & Administration**
### **Recommended Dosage**
**Adults:** Use **one 120 ml bottle once daily**, or as directed by your physician.
### **Administration**
* **For rectal use only.**
* The product should be administered while lying on the **left side with both knees slightly bent**, unless otherwise instructed by a healthcare professional.
* Use only as directed. Do not exceed the recommended dosage.
---
## **Warnings & Precautions**
* Do not use if you have **severe abdominal pain, nausea, vomiting, intestinal obstruction, acute gastrointestinal disorders, congestive heart failure, or severe kidney disease**, unless advised by your physician.
* Avoid prolonged or frequent use, as excessive use may result in dehydration, electrolyte imbalance, or dependence on laxatives.
* If constipation persists after use or symptoms worsen, discontinue use and consult your healthcare provider.
* Keep out of the reach of children.
---
## **Possible Side Effects**
Most users tolerate Instant Enema well; however, some may experience:
* Mild abdominal discomfort or cramping
* Temporary rectal irritation
* Gas or bloating
In rare cases, repeated or excessive use may lead to **electrolyte disturbances** or **laxative dependence**. Seek medical advice if severe or persistent side effects occur.
---
## **Age Restriction**
Instant Enema is **not generally recommended for children under 2 years of age** unless specifically prescribed by a physician.
---
## **Storage Instructions**
Store in a cool, dry place at room temperature, away from direct sunlight and excessive heat. Do not freeze. Keep the bottle tightly closed until ready for use.
Itrazox 100mg ( Itraconazole ) Maxitech
Itraconazole Used For Fungal Infection
Itraconazole is used to treat yeast infections of the mouth and throat or of the esophagus (tube that connects the throat to the stomach). Itraconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection.
Itrazox Capsules Usage And Safety
Dosage
Itraconazole
Side Effects
Granulocytopenia, Thrombocytopenia , Hyperglycemia, Hyperkalemia, Hypokalemia, Hypomagnesemia , Confusional state , Neuropathy peripheral, Dizziness, Somnolence , Cardiac failure, Left ventricular failure, Tachycardia , : Hypertension, Hypotension , Gastrointestinal disorder , Hepatic failure, Hepatitis, Jaundice , Rash erythematous, Hyperhidrosis , Myalgia, Arthralgia , : Generalized edema, Face edema, Chest pain, Pyrexia, Pain, Fatigue, Chills .
Drug Interactions
Itraconazole : Rifampicin , cyclosporin , H2 antagonists , antacids , tamsulosin , antiarrhythmics , digoxin , cilosrazole , repaglinide , saxagliptin , midazolam , nadolol , tacrolimus , salmeterol , reboxetine , statins , tolvaptan , meloxicam , sirolimus , domperidone , ivabradine, ergot alkaloids.
Indication
It is used for infections caused by fungi or yeasts such as vaginal infections, dermatological infections, onychomycosis etc.
When not to Use
It is contraindicated in patients with known hypersensitivity to itraconazole or to any of the excipients.
Itrazox Capsules Precautions
Precaution
When driving vehicles and operating machinery the possibility of adverse reactions such as dizziness, visual disturbances and hearing loss , which may occur in some instances, must be taken into account.
Itrazox Capsules Warnings
Warning 1
Itraconazole has been shown to have a negative inotropic effect and it has been associated with reports of CHF.
Warning 2
There is limited information regarding cross-hypersensitivity between itraconazole and other azole antifungal agents. Caution should be used in prescribing itraconazole capsules to patients with hypersensitivity to other azoles.
Warning 3
The use of capsules in pediatric patients is not recommended unless it is determined that the potential benefit outweighs the potential risks.
Itrazox Capsules Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
IZMEPRA 40MG CAP (Omeprazole 40mg) – EPHARM LABORATORIES
# **Izmepra Capsules (Esomeprazole)**
## **Common Uses**
Izmepra contains **Esomeprazole**, a proton pump inhibitor (PPI) that reduces the production of stomach acid. It is used in the treatment and management of various acid-related gastrointestinal disorders, including:
* **Gastroesophageal Reflux Disease (GERD):** Relieves symptoms such as heartburn and acid reflux while promoting the healing of erosive esophagitis.
* **Gastric and Duodenal Ulcers:** Used for the treatment and prevention of ulcers, including those associated with *Helicobacter pylori* infection (in combination with appropriate antibiotics) and ulcers caused by prolonged NSAID use.
* **Zollinger-Ellison Syndrome:** Helps control excessive gastric acid secretion in patients with this rare condition.
---
## **How It Works**
Esomeprazole works by blocking the **proton pumps** in the stomach lining that produce acid. By reducing acid secretion, it allows ulcers to heal, relieves reflux symptoms, and helps prevent further damage to the esophagus and stomach.
---
## **Usage & Safety**
### **Administration**
* Take the capsule **exactly as prescribed** by your physician.
* Swallow the capsule **whole with water**.
* Do **not** crush, chew, or open the capsule, as this may affect its effectiveness.
* For optimal results, it is generally recommended to take the medicine **before a meal**, preferably in the morning.
---
## **Possible Side Effects**
Izmepra is generally well tolerated. However, some individuals may experience:
* Headache
* Abdominal pain
* Diarrhea
* Constipation
* Nausea
* Flatulence
These side effects are usually mild and temporary. Consult your physician if they persist or become troublesome.
---
## **Warnings & Precautions**
* Long-term use (particularly **longer than 3 months**) may increase the risk of **low magnesium levels**, **Vitamin B12 deficiency**, and **bone fractures** in some patients.
* Inform your physician if you have liver disease, osteoporosis, or are taking other long-term medications.
* Seek immediate medical attention if you develop signs of an allergic reaction, including **difficulty breathing, swelling of the face, lips, tongue, or throat, or severe skin rash**.
* Use only under the supervision of a qualified healthcare professional.
---
## **Storage Instructions**
Store below **30°C** in a cool, dry place, away from direct sunlight and moisture. Keep out of the reach of children.
kemadrin 5mg tablet ( Procyclidine ) GSK
If you are taking this medication for side effects from another medication, your doctor may instruct you to take it on a regular schedule or only as needed. If you are taking this medication for Parkinson's disease, your doctor may change the dose of your other medications (such as levodopa). Follow your doctor's instructions closely. Do not stop or change the dose of your medication without your doctor's approval.
Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.
When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.
Tell your doctor if your condition lasts or gets worse.
Ketosteril Tablet ( Ketoanalogues + Essential Amino Acids ) fresenius kabi
Ketosteril is used to prevent and preserve patients with chronic renal failure with a glomerular filtration rate of 5-15 ml/min. The drug is used in combination with a restricted protein diet (protein intake 40g per day in adults or less)
The drug helps to relieve symptoms caused by uremia, reduce proteinuria, prevent protein breakdown of the body, correcting disorders of calcium-phosphate metabolism, hyperparathyroidism and renal osteoporosis, helping to improve carbohydrate metabolism disorders, lipid metabolism, and endocrine disorders.
Ketosteril allows the body to take in essential amino acids while minimizing nitrogen-nitrogen intake. Once absorbed into the body, the keto- and hydroxy analogues will be converted to essential amino acids by taking nitrogen from the non-essential amino acids, thereby reducing urea formation by using amine group.
Therefore, the accumulation of uraemia toxins is reduced. Keto and hydroxy acids do not induce ultrafiltration in the remaining nephrons. Ketosteril contains a supplement that promotes a positive effect on renal hyperphosphatemia and secondary hyperparathyroidism.
Furthermore, renal osteodystrophy may be improved with the use of Ketosteril. The use of Ketosteril in combination with a very low protein diet reduces nitrogen intake to prevent serious consequences of protein supplementation in patients with renal failure.
How to use Ketosteril:
Use Ketosteril as prescribed by your doctor. Do not arbitrarily increase, decrease the dose or prolong the time of using Ketosteril compared to the indicated. Take Ketosteril tablets with food, do not chew the medicine. During the use of Ketosteril drug, it is necessary to monitor the amount of protein taken into the body. Before dialysis, protein intake should not exceed 40g/day for adults; for children from 3-10 years old: 1.4-0.8g/kg; for children 10 years and older: 1-0.6g/kg.. You should consult your doctor during dialysis.
Kleen Enema ( Sodium Biphosphate , Sodium Phosphate ) Nabiqasim Industries
This medication is indicated in patients with constipation and bowel clearence.
Pregnancy:
During pregnancy this medication should only be used when clearly needed. Consult your doctor before using this medication.
Lactation:
No definite data regarding lactating females is available, therefore; be cautious. Consult your doctor before using this medication.
Contraindications:
This medication is contraindicated in patients with acute GI conditions, GI obstruction, abdominal pain, nausea, vomiting, renal (kidney) failure, congestive heart failure.
Precautions:
Elderly and weak patients. restricted sodium intake, renal (kidney) impairment, heart disease and colostomy (surgical procedure).
Adverse effects:
Patients administered with this medication may experience mild abdominal discomfort or gas may occur.
Primary Uses
Constipation
Indications
This medication is indicated in patients with constipation and bowel clearence.
Side Effects
Patients administered with this medication may experience mild abdominal discomfort or gas may occur.
Warnings
Pregnancy
During pregnancy this medication should only be used when clearly needed. Consult your doctor before using this medication.
Lactation
No definite data regarding lactating females is available, therefore; be cautious. Consult your doctor before using this medication.
Driving
Please avoid driving when taking this medicine as it may affect your ability to drive.
Precautions
Elderly and weak patients. restricted sodium intake, renal (kidney) impairment, heart disease and colostomy (surgical procedure).
Contraindications
This medication is contraindicated in patients with acute GI conditions, GI obstruction, abdominal pain, nausea, vomiting, renal (kidney) failure, congestive heart failure.
FAQS
Uses:
This medication is used for treating severe constipation. It helps soften stools and increases the number of bowel movements, making passing stools easier. It can also be used to clean the intestines before and surgery or medical procedure. This medicine is not recommended for children less than two years of age.
Storage:
Please read the leaflet provided with the medicine for storage guidance. Keep medicine away from excessive light, moisture, and children. Please do not flush medicines down the toilet.
Side Effects:
You may experience the following: • Gas • Abdominal discomfort
Precautions:
Following are the precautions for using this medicine: • You may develop dependency therefore use Enema Liquid only when absolutely necessary • Drink plenty of water to prevent dehydration • Children may be more sensitive to the side effects
Will I see instant results?
It may take up to 30 minutes for this medicine to work effectively.
Effects on pregnancy and lactation:
This medicine should only be used during pregnancy if no safer alternate is available. The effects of this medicine on lactating females are unknown. Consult your health care provider before use of this medicine.
Kofarex Z Syrup (Hedera hilex) – Nutrabiotics
Kofarex-Z Cough Syrup 120ml Description
Kofarex-Z Cough Syrup is a herbal cough remedy formulated with Hedera Helix (Ivy Leaf Extract) to provide effective relief from cough and chest congestion. Its natural formula helps loosen and clear mucus from the airways, making breathing easier while soothing throat irritation. Suitable for both children and adults (as directed by a healthcare professional), Kofarex-Z supports respiratory comfort by relieving productive coughs and promoting easier expectoration. With its pleasant raspberry flavour, it offers a convenient and effective solution for everyday cough relief.
KRAZOR PREWORKOUT (FLAVOR= GREEN APPLE) – Hyplift Nutrition
Built for beginners and everyday athletes, the enhanced KRAZOR Pre-Workout delivers a smoother taste, balanced performance, and sustained clean energy—without the crash.
Powered by Green Coffee and Red Ginseng, KRAZOR helps boost focus, increase energy, and support peak performance throughout your workout.
Same purpose. Better performance.
Lasix Injection 20mg 50 x 2ml ampoules (Furosemide) – Sanofi
Heart Failure
How it works
It has been demonstrated that Furosemide inhibits primarily the absorption of sodium and chloride not only in the proximal and distal tubules but also in the loop of Henle. The high degree of efficacy is largely due to the unique site of action. The action on the distal tubule is independent of any inhibitory effect on carbonic anhydrase and aldosterone.
Usage And Safety
Dosage
Oedema : Adults : Treatment is usually begun with 20-80mg as single dose daily or an alternate days . Children : Usual : 2mg/kg as single dose , may increase by 1-2mg/kg after 6-8 hr . Max : 6mg/kg. Heart Failure : Adults : Usual : 20-80mg as a single dose , may repeat or increase by 20-40mg after 6-8hr . Max : 600mg/dday . Hypertension : Adults : Initial : 40mg twice daily . Maintenance : Adjust according to response . OR As directed by your physician .
Side Effects
Gastrointestinal System Reaction : Hepatic encephalopathy in patients with oral and gastric irritation hepatocellular insufficiency , cramping , pancreatitis , diarrhea , jaundice (intrahepatic cholestatic jaundice) , constipation , increased liver enzymes , nausea , anorexia , vomiting ; Systemic Hypersensitivity Reactions : Severe anaphylactic or anaphylactoid , interstitial nephritis reactions (e.g. with shock) , necrotizing angiitis , systemic vasculitis ; Central Nervous System Reactions , tinnitus and hearing loss , dizziness , paresthesias , headache , vertigo , blurred vision , xanthopsia .
Drug Interactions
Aminoglycoside antibiotics , ethacrynic acid , cisplatin , tubocurarine , Lithium , angiotensin converting enzyme inhibitors or angiotensin II receptor blockers , norepinephrine , sucralfate , Phenytoin , Methotrexate , cephalosporin , cyclosporine .
Indication
It is use in : ? Fluid retention associated with chronic congestive cardiac failure (if diuretic treatment is required). ? Fluid retention associated with acute congestive cardiac failure. ? Fluid retention associated with chronic renal failure. ? Maintenance of fluid excretion in acute renal failure, including that due to pregnancy or burns. ? Fluid retention associated with nephrotic syndrome (if diuretic treatment is required). ? Fluid retention associated with liver disease (if necessary to supplement treatment with aldosterone antagonists). ? Hypertension. ? Hypertensive crisis (as a supportive measure). ? Support of forced diuresis.
When not to Use
It must not be used: ? In patients with hypersensitivity to furosemide or any of the excipients . Patients allergic to sulfonamides (e.g. sulfonamide antibiotics or sulfonylureas) may show crosssensitivity to furosemide . ? In patients with hypovolaemia or dehydration. ? In patients with anuric renal failure not responding to frusemide. ? In patients with severe hypokalaemia ? In patients with severe hyponatraemia .
Precautions
Precaution
In patients with partial obstruction of urinary outflow (e.g in patients with bladder – emptying disorders, prostatic hyperplasia, narrowing of the urethra) increased production of urine may provoke or aggravate complaints. Thus, these patients require careful monitoring - especially during the initial stages of treatment.
Warnings
Regular monitoring of serum sodium, potassium and creatinine is generally recommended during furosemide therapy; particularly close monitoring is required in patients at high risk of developing electrolyte imbalances or in case of significant additional fluid loss (e.g. due to vomiting, diarrhoea or intense sweating). Hypovolaemia or dehydration as well as any significant electrolyte and acid-base disturbances must be corrected. This may require temporary discontinuation of furosemide .
Patients allergic to sulfonamides may also be allergic to furosemide. The possibility exists of exacerbation or activation of systemic lupus erythematosus.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat
Lemin 500mg Tablet (Levofloxacin) – Amros Pharma
# **Lemin Tablets (Levofloxacin)**
## **How It Works**
Lemin contains **Levofloxacin**, a broad-spectrum fluoroquinolone antibiotic that works by inhibiting bacterial DNA replication, ultimately stopping the growth of bacteria and eliminating the infection.
**Note:** Lemin is effective **only against bacterial infections** and should not be used to treat viral illnesses such as the common cold or influenza.
---
## **Indications**
Lemin is indicated for the treatment of susceptible bacterial infections, including respiratory tract, urinary tract, skin, and other infections, as prescribed by your physician.
---
## **Usage & Safety**
### **Prescription Status**
Lemin is a **prescription-only medicine** and should be used strictly under the supervision of a qualified healthcare professional.
### **Dosage & Administration**
* Take **once daily**, or exactly as prescribed by your physician.
* Swallow the tablet whole with a **full glass of water**.
* It may be taken **with or without food**.
* Take the medicine at the **same time each day** for the best therapeutic effect.
### **Drug Interactions**
Avoid taking Lemin **within 2 hours before or after** products containing **aluminum, magnesium, calcium, iron, or zinc**, including antacids, multivitamins, and mineral supplements, as these may reduce the absorption and effectiveness of Levofloxacin.
### **Complete the Full Course**
Continue taking the medication for the **entire prescribed duration**, even if you begin to feel better. Stopping treatment too early may allow the infection to return and contribute to **antibiotic resistance**.
---
## **Possible Side Effects**
Lemin is generally well tolerated; however, some patients may experience:
* Nausea
* Diarrhea or constipation
* Headache
* Dizziness
* Difficulty sleeping (insomnia)
These side effects are usually mild and temporary. If they persist or become severe, consult your physician.
---
## **Warnings & Precautions**
* Use Lemin only for **confirmed or strongly suspected bacterial infections**.
* Discontinue the medication and seek immediate medical attention if you experience signs of an allergic reaction, severe diarrhea, tendon pain or swelling, numbness, tingling, or irregular heartbeat.
* Inform your physician if you have a history of **kidney disease, epilepsy, tendon disorders, or heart rhythm abnormalities** before starting treatment.
* Avoid unnecessary exposure to direct sunlight or UV light during therapy, as Levofloxacin may increase **photosensitivity**.
---
## **Storage Instructions**
Store below **30°C** in a cool, dry place, protected from direct sunlight and moisture. Keep out of the reach of children.
Lets Tablets 2.5mg (Letrozole) -genix pharma
Used For
Letrozole 2.5mg Tablets are primarily used for the treatment of hormone receptor-positive breast cancer in postmenopausal women. They may also be prescribed before surgery or after other hormone therapies as recommended by an oncologist.
How It Works
Letrozole belongs to the class of medicines known as aromatase inhibitors. It works by blocking the aromatase enzyme responsible for producing estrogen in the body. Lower estrogen levels help slow or stop the growth of hormone-sensitive breast cancer cells while having minimal effects on other hormone-producing glands.
Usage & Safety
Dosage
The usual adult dose is one 2.5mg tablet once daily, with or without food. Take the medicine at the same time each day for the best results. Always use it exactly as prescribed by your doctor.
Possible Side Effects
Some people may experience:
Hot flushes
Headache
Dizziness
Fatigue
Joint or muscle pain
Nausea
Constipation or diarrhea
Increased sweating
Weight changes
Hair thinning
High cholesterol
Osteoporosis or reduced bone density
Swelling of the hands or feet
Seek immediate medical attention if you develop chest pain, difficulty breathing, severe allergic reactions, blood clots, or signs of liver problems.
Drug Interactions
Tell your healthcare provider if you are taking:
Tamoxifen
Warfarin
Cimetidine
Other hormonal therapies
Prescription, non-prescription, or herbal medicines
Indications
Letrozole is commonly prescribed for:
Early-stage hormone receptor-positive breast cancer
Advanced or metastatic breast cancer
Adjuvant treatment after surgery
Extended therapy following Tamoxifen treatment
Neoadjuvant therapy before surgery in selected patients
When Not to Use
Do not use Letrozole if:
You are allergic to Letrozole or any of its ingredients.
You are pregnant or breastfeeding.
You have not yet reached menopause unless specifically advised by your doctor.
Precautions
Inform your doctor before using Letrozole if you have:
Osteoporosis or a history of bone fractures
Liver disease
Kidney impairment
High cholesterol
Heart disease
Regular monitoring of bone health and cholesterol levels may be required during treatment.
Warning
Long-term use may reduce bone mineral density and increase the risk of osteoporosis or fractures. Your doctor may recommend regular bone density tests.
Blood cholesterol levels may increase during treatment. Periodic lipid profile monitoring is recommended.
Patients with severe liver impairment may require dose adjustments and close medical supervision.
Additional Information
Pregnancy
Letrozole should not be used during pregnancy or while breastfeeding. Always consult your healthcare provider before taking this medicine.
Storage
Store below 30°C in a cool, dry place away from direct sunlight, moisture, and heat. Keep out of the reach of children.