Primolut N Tablet (Norethisterone) – Bayer
Primolut-N Tablet is used to treat various menstrual problems including painful, heavy, or irregular periods, premenstrual syndrome (PMS) and a condition called endometriosis. It is a man-made version of the natural female sex hormone progesterone.
Primolut-N Tablet may be taken with or without food, but it is better to take it at the same time each day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need so as to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed to you.
The most common side effects of this medicine include headache, nausea, abdominal pain, vaginal spotting, dizziness, and breast tenderness. Let your doctor know if these bother you or appear serious, as there may be ways of reducing or preventing them. Some side effects may mean you should stop taking this medicine, including if you develop jaundice, migraine, or changes to your speech or senses (eyesight, hearing, smell, taste, and touch). You should also stop taking it if you become pregnant or if your blood pressure becomes too high.
Before taking this medicine, tell your doctor if you are pregnant or breastfeeding, have diabetes, have a migraine, or any liver disease or ever had any problems with your blood circulation. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. This medicine can affect the results of some blood and urine tests so make sure any doctor treating you knows that you are taking it.
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KENACOMB reduces inflammation, relieves pruritis and combats or prevents monilial and bacterial infections.
Pharmacokinetics
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin increase percutaneous absorption.
Nystatin and gramicidin are not absorbed from intact skin or mucous membranes.
Neomycin can be absorbed through inflamed skin. Once absorbed, it is rapidly excreted unchanged through the kidneys. The half-life is approximately 2 to 3 hours.
Microbiology
Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components.
Nystatin exhibits no activity against bacteria, protozoa, or viruses.
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INDICATIONS
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