Clopixol Acuphase (100Mg/2Ml) (Zuclopenthixol) – Lundbeck

Mechanism of Action

Zuclopenthixol works primarily by blocking dopamine D1 and D2 receptors in the brain. It also has a high affinity for alpha₁-adrenergic and 5-HT₂ (serotonin) receptors, helping to reduce psychotic symptoms and stabilize mood.

Active Ingredient

Zuclopenthixol

Drug Class

Antipsychotic

Dosage Form

Injection

Uses

Zuclopenthixol Injection is commonly used for:

• Treatment of schizophrenia and other psychotic disorders.
• Relief of symptoms such as hallucinations, delusions, and disturbed thinking.
• Management of acute manic episodes associated with bipolar disorder.
• Treatment of severe behavioral disturbances, including aggression, agitation, and disruptive behavior in selected pediatric patients, as prescribed by a physician.

Dosage

Use only as directed by your physician. The dosage and duration of treatment depend on your medical condition and response to therapy.

Overdose

In case of an overdose, seek immediate medical attention or contact your nearest emergency medical facility.

Missed Dose

If you miss a scheduled dose, take it as soon as possible on the same day. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for the missed one.

How to Use

This medicine should be administered exactly as prescribed by your healthcare professional. Do not change the dose or discontinue treatment without medical advice.

When Not to Use

Do not use this medicine if you are allergic to zuclopenthixol or any of its ingredients.

Side Effects

Common side effects may include:

• Drowsiness or sedation
• Weakness or fatigue
• Constipation
• Increased triglyceride levels
• Enlarged prostate
• Parkinson-like symptoms (muscle stiffness, tremors, or slowed movement)
• Low platelet count (thrombocytopenia)
• Increased risk of pneumonia
• Seizures

Precautions & Warnings

Use this medicine with caution in patients with cardiovascular disease, seizure disorders, Parkinson’s disease, or liver impairment. Seek immediate medical attention if you experience signs of an allergic reaction, severe muscle stiffness, irregular heartbeat, or unusual involuntary movements. Regular medical monitoring may be required during treatment.

Drug Interactions

Zuclopenthixol may interact with:

• Antidepressants
• Other antipsychotic medicines
• Beta-blockers
• Central nervous system (CNS) depressants
• Lithium

Inform your doctor about all medicines, vitamins, and herbal supplements you are taking before starting treatment.

Storage

Store at room temperature, away from heat, moisture, and direct sunlight. Keep out of the reach of children. Dispose of unused or expired medicine according to local regulations.

Controlled Drug

No