Zyrtec Tablet (Cetirizine) – gsk
Cetirizine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
Cetirizine does not prevent hives or prevent/treat a serious allergic reaction (such as anaphylaxis). Therefore, if your doctor has prescribed epinephrine to treat allergic reactions, always carry your epinephrine injector with you. Do not use cetirizine in place of your epinephrine.
Zyrtec (cetirizine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Zyrtec is used in adults and children to treat cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose.
Zyrtec is also used to treat itching and swelling caused by chronic urticaria (hives).
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This medication is used to treat sudden diarrhea (including traveler’s diarrhea). It works by slowing down the movement of the gut. This decreases the number of bowel movements and makes the stool less watery. Loperamide is also used to reduce the amount of discharge in patients who have undergone an ileostomy.
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The complete list of uses and indications for Entamizole Tablet is as follows:
Stomach infection
Intestinal infection
Amoebiasis
Abdominal infections
Antibiotic associated colitis
Peptic ulcer disease
Genital tract infection
Balantidiasis
Brain infection
Blood infection
Amebic colitis
Ulcerative gingivitis
Blastocysts hominies infection
Giardiasis
Infections of gum and dental cavities
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Pressure sores
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Infections after surgery
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Kenacomb Cream – GSK
KENACOMB combines the potent corticosteroid triamcinolone acetonide with the antifungal antibiotic nystatin and the wide spectrum antibacterial activity of neomycin and gramicidin.
KENACOMB reduces inflammation, relieves pruritis and combats or prevents monilial and bacterial infections.
Pharmacokinetics
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin increase percutaneous absorption.
Nystatin and gramicidin are not absorbed from intact skin or mucous membranes.
Neomycin can be absorbed through inflamed skin. Once absorbed, it is rapidly excreted unchanged through the kidneys. The half-life is approximately 2 to 3 hours.
Microbiology
Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components.
Nystatin exhibits no activity against bacteria, protozoa, or viruses.
Neomycin exerts its bacterial activity against a number of gram-negative organisms by inhibiting protein synthesis. It is not active against Pseudomonas aeruginosa, and resistant strains of gram-negative bacteria may develop.
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INDICATIONS
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Atopic dermatitis
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Psoriasis (particularly of the face and body folds)
Allergic contact dermatitis
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